3rd International Conference on Retroviruses and Novel Drugs July 27-28, 2017 Vancouver, Canada

   Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. Different classes of antiretroviral drugs act on different stages of the HIV life cycle. Combination of several (typically three or four) antiretroviral drugs is known as highly active anti-retroviral therapy.

The care of the human immunodeficiency virus (HIV) infected patient has changed dramatically in the last few years. Potent new antiretroviral drugs combined with updated treatment strategies have now achieved efficient inhibition of HIV replication in most patients.  It is clear that the eradication of HIV is not achievable with existing anti-HIV drugs and in spite of the major advances there remain many challenges in the clinical management of HIV-infected individuals.

Retroviruses are an efficient means to deliver single DNA expression constructs to a wide range of mammalian cell types. They are by far the easiest and fastest means to deliver genes stably to mammalian cells. They have an additional advantage in that systems developed application to deliver large libraries of genes or peptides to target cells.

Acute HIV infection and primary HIV infection both describe the period immediately after infection when the patient is viremic and has detectable HIV RNA without diagnostic HIV antibodies.  Early infection refers to both acute and recent infection, after which infection is defined as chronic.

Endogenous viral elements in the genome that closely resemble and can be derived from retroviruses and exogenous retroviruses such as human immunodeficiency virus (HIV) and human T cell leukaemia virus.

Osteoporosis is a disease that causes bones to become weak and easy to break. Osteoporosis increases the risk of fractures of the hip, spine, and wrist. Factors that may increase the risk of osteoporosis in people living with HIV include HIV infection itself and some HIV medicines.

HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy.

A retrovirus vector is an infectious virus used to introduce a nonviral gene into mitotic cells in vivo or in vitro.  Transduction does not require physical contact between the cell donating the DNA and the cell receiving the DNA and it is DNase resistant. Transduction is a common tool used by molecular biologists to stably introduce a foreign gene into a host cell's genome.

HIV is one of the best-known retroviruses. Oncogenic retroviruses are cancer-causing viruses. Numerous oncoretroviruses are associated with animal diseases. In humans, two retroviruses, called HTLV and XMRV, have been associated with a type of leukemia and with prostate cancer.

Some infectious diseases can be passed from person to person. Signs and symptoms vary depending on the organism causing the infection. Human Papilloma Virus is the most common sexually transmitted diseases. Some types of these viruses can cause genital warts and cancers. Genital warts usually appear as a small bump or group of bumps in the genital area. However, if the infection is High risk, then there will be more chances of occurrence of cervical cancer. Vaccination is recommended for the patients with compromised immune system.

Antiretroviral therapy has been exceeding by adapting the various novel drug delivery methods, which pays pathway for many scientists to prove the efficiency of their techniques. The formulation design and optimization of analytical techniques requires multidisciplinary research for ultimate marketing of these NDDS products especially for ARV drugs, because of the intricacy of the viral infections diseases. Certainly, the present techniques with new therapeutic agents and scheduled regimens can provide notice able improvement in the future of HIV virus infected people’s living.