Corrado Spadafora
Institute of Translational Pharmacology, CNR National Resarch Council of Italy, Rome, Italy
Biography
Corrado Spadafora's laboratory originally discovered that mature sperm cells from a variety of species share the ability to spontaneously take up exogenous DNA molecules and deliver them to oocytes at fertilization: they called that phenomenon cell-mediated sperm-mediated gene transfer (SMGT). That feature was subsequently exploited, in theirs and other laboratories, to generate genetically modified animals in different species.
Abstract
Abstract : A Reverse Transcriptase-dependent mechanism is active in embryo development and in tumorigenesis
