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James A Shapiro

James A Shapiro

University of Chicago, USA

Title: Retroviruses and the RW Genome

Biography

Biography: James A Shapiro

Abstract

The RW Genome means that cells actively inscribe information onto and into their DNA. In real time, these inscriptions include nucleoprotein complexes and epigenetic chromatin modifications. Over evolutionary time, natural genetic engineering functions rearrange and incorporate new information into the DNA. Retroviruses are key components of the genetic engineering toolbox. In the course of mammalian and human evolution, they have played important roles, including contributions to the origination of the placenta and pregnancy. The lecture will highlight how retroviruses contribute into genome content and regulatory formatting.

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